Tolerance to etoricoxib in children with nonsteroidal anti-inflammatory drug hypersensitivity

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Tolerance to etoricoxib in children with nonsteroidal anti-inflammatory drug hypersensitivity

BACKGROUND Cyclooxygenase-2 (COX-2) inhibitors have been found to be safe alternatives in adults with cross-intolerant hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs). However they are usually not prescribed in children and there is little information about their tolerance in the pediatric age group. OBJECTIVE This study aims to evaluate the tolerance to etoricoxib in childr...

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Nonsteroidal Anti-Inflammatory Drug Hypersensitivity in Preschool Children

: Although extensively studied in adults, nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity in children, especially in young children, remains poorly defined. Pediatricians, prescribing antipyretics for children, rarely encounter significant problems, but the few epidemiologic studies performed show conflicting results. Although it is clear that some patients with acetylsalicylic aci...

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Meloxicam tolerance in hypersensitivity to nonsteroidal anti-inflammatory drugs.

BACKGROUND Patients with aspirin-sensitive respiratory and skin diseases experience cross reactions to all nonsteroidal anti-inflammatory drugs (NSAIDs) which inhibit cyclooxigenase (COX) enzymes. The need to identify an alternative drug that is safe and reliable is a common problem in clinical practice. OBJECTIVE The aim of this study was to test the tolerability of meloxicam in NSAID-sensit...

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Clinical Management of Nonsteroidal Anti-inflammatory Drug Hypersensitivity

Hypersensitivity diseases caused by nonsteroidal anti-inflammatory agents are relatively common in the population. This article summarizes the present understanding on the various allergic and nonallergic clinical pictures produced through hypersensitivity to these drugs using the pathogenic classification of hypersensitivity reactions recently proposed by the Nomenclature Committee of the Worl...

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What we know about nonsteroidal anti-inflammatory drug hypersensitivity

Nonsteroidal anti-inf lammatory drugs (NSAIDs) are widely prescribed for the treatment of inflammatory diseases, but their use is frequently related to hypersensitivity reactions. This review outlines our current knowledge of NSAID hypersensitivity (NHS) with regard to its pathogenic, molecular, and genetic mechanisms, as well as diagnosis and treatment. The presentation of NHS varies from a lo...

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ژورنال

عنوان ژورنال: Asia Pacific Allergy

سال: 2015

ISSN: 2233-8276,2233-8268

DOI: 10.5415/apallergy.2015.5.1.40